Clinical manifestations and cerebrospinal fluid status in ocular syphilis in HIV-Negative patients
نویسندگان
چکیده
منابع مشابه
Clinical manifestations and cerebrospinal fluid status in ocular syphilis in HIV-Negative patients
BACKGROUND Syphilis with ocular involvement has reemerged as a critical health problem. The aim of the present study was to explore the clinical manifestations and cerebrospinal fluid (CSF) status in ocular syphilis in human immunodeficiency virus (HIV)-negative patients. METHODS The clinical records of patients with ocular syphilis presenting to the Shanghai Xuhui Central Hospital in the per...
متن کاملThe Cerebrospinal Fluid in Syphilis
The results presented in this communication are based on the examination of 113 cases of syphilis in all stages of the disease, from the secondary eruption to general paresis. During the past ten months every case of syphilis admitted to the hospital has had lumbar puncture performed as part of the routine examination; previous to that time only cases which suggested infection of the nervous sy...
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Lumbar puncture in neurologically asymptomatic HIV+ patients is still under debate. There are different criteria for detecting neurosyphilis through cerebrospinal fluid (CSF), especially in cases that are negative through the Venereal Disease Research Laboratory (VDRL), regarding cellularity and protein content. However, a diagnosis of neurosyphilis can still exist despite negative VDRL. Trepon...
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The concentrations of immunoglobulins G, A, and M were measured in 62 samples of cerebrospinal fluid from 35 patients with asymptomatic neurosyphilis, 18 with symptomatic neurosyphilis, and nine with late syphilis of other organs. The most frequent and highest increase in IgG and IgA occurred in patients with symptomatic neurosyphilis. IgM was found in only five patients, but its presence, toge...
متن کاملCerebrospinal fluid abnormalities in patients with syphilis: association with clinical and laboratory features.
OBJECTIVE To define clinical and laboratory features that identify patients with neurosyphilis. METHODS Subjects (n=326) with syphilis but no previous neurosyphilis who met 1993 Centers for Disease Control and Prevention criteria for lumbar puncture underwent standardized history, neurological examination, venipuncture, and lumbar puncture. Neurosyphilis was defined as a cerebrospinal fluid (...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2016
ISSN: 1471-2334
DOI: 10.1186/s12879-016-1586-z